TREATMENT OF LYME DISEASE WITH HYPERBARIC OXYGEN THERAPY
From: Undersea & Hyperbaric Medicine, volume 25, 1998 supplement
By W. P. Fife, DM Freeman.
Texas A&M university Health Science Center
College Station, TX 77843-1264
BACKGROUND: It has been shown that the spirochete, Borrelia burgdorferi is a facultative anaerobic organism which can survive in an oxygen partial pressure of 35 mm Hg, but not in an oxygen partial pressure of 160 mm Hg. When Lyme disease becomes chronic and the spirochete is sequestered in cells, the cells may protect the spirochete against the antibiotic, which then is not fully effective. Spirochete survival after more than 15 years of antibiotic therapy is known.
METHOD: Subjects were exposed to an ambient pressure of 2.36 ata (45fw) for a period of 60 minutes per treatment in a multi place chamber. Treatments usually were administered twice each day for a total of from 10 to 125 exposures resulting in an oxygen partial pressure at the tissue level of approximately 200-mm Hg.
RESULTS: The study included 90 subjects, all of whom had failed IV antibiotics some for as long as 5 years and who were continuing to deteriorate. All presented with Jarisch-Herxheimer’s reaction within 4 days of beginning HBO. All except 4 subjects showed significant improvement after termination of the treatment regimens. Approximately 70% continued to feel well after recovery while others had some relapse but showed further improvement with re-treatment.
CONCLUSION: No cure is claimed by this treatment even though many who have completed the regimen remain essentially well or are much improved. It is clear that this treatment improves the quality of life after all other treatments have failed.